Simone Zaza struck twice as Sassuolo beat 10-man Genoa 3-1 on Sunday to finish their Serie A campaign on a high.
Fiorentina qualified for the Europa League while Stephan El Shaarawy scored his first goal in seven months for AC Milan.
Liverpool give U21s more game time than Premier League rivals but top flight lags behind Europe.
Sassuolo defeated 10-man Udinese 1-0 on Sunday afternoon to continue their strong finish to the season.
Domenico Berardi's hat-trick fired Sassuolo to a 3-2 victory over nine-man AC Milan on Sunday afternoon.
Napoli's hopes of Champions League qualification suffered a setback as they drew 2-2 at rock-bottom Parma in Serie A on Sunday.
Cesena's relegation from Serie A was confirmed as they let a two-goal lead slip to lose 3-2 at home to Sassuolo.
Sassuolo and Palermo shared the spoils in a 0-0 draw on Saturday evening.
Roma tightened their grip on the last Champions League place with a 3-0 triumph at Sassuolo on Wednesday evening.
Luca Toni struck twice in the second half to fire 10-man Hellas Verona to a 3-2 home triumph over Sassuolo.
Fabio Quagliarella struck from the penalty spot as Torino came from behind to earn a 1-1 draw at Sassuolo.
German Denis struck twice as relegation-threatened Atalanta beat Sassuolo 2-1 at home on Sunday.
Domenico Berardi struck from the penalty spot to hand 10-man Sassuolo a 1-0 home triumph over Chievo.
Juventus closed in on a fourth straight Serie A title after a 2-0 victory over Empoli.
Empoli climbed above Sassuolo in the Serie A standings thanks to a 3-1 win at the Stadio Carlo Castellini on Sunday.
Veteran striker Luca Toni scored in either half as Verona pulled off a surprise 2-0 win over Napoli on Sunday.
Nicola Sansone scored twice in the first half as Sassuolo hammered 10-man Parma 4-1 on Sunday.
Paul Pogba's late goal gave Juventus a 1-0 win over Sassuolo to send them 11 points clear in Serie A.
Juventus opened up an 11-point lead at the top of Serie A with 12 games to go thanks to a 1-0 win over Sassuolo.
Napoli missed the chance to move level with second-placed Roma in Serie A as they lost 1-0 at Torino on Sunday.