Davinson Sanchez and Kasper Dolberg both scored twice as Ajax beat Zwolle 5-1 while PSV won at Excelsior.
Eric Botteghin struck a late winner as Feyenoord maintained their perfect start to the Eredivisie season with a 1-0 win at PSV.
Dundalk manager Stephen Kenny admits his side are seen as outsiders as they prepare to face AZ Alkmaar in the Europa League.
Luuk de Jong capped a 24-minute blitz as PSV stormed back to the top of the Eredivisie with a 4-1 win over NEC in Nijmegen.
Hull have signed AZ Alkmaar's Norway international Markus Henriksen on a season-long loan.
PSV Eindhoven surrendered their 100 per cent record in disappointing fashion after being held to a 0-0 draw at home to Groningen.
Man Utd will face Fenerbahce, Feyenoord and Zorya Luhansk in the Europa League, while Southampton are in a group with Inter Milan.
Feyenoord continued their perfect start to the season and returned to the top of the Eredivisie with a 1-0 win at Heracles Almelo.
Eredivisie champions PSV made it two wins from two as Hector Moreno's goal secured a 1-0 victory over AZ Alkmaar, on Sunday.
Eljero Elia's hat-trick helped Feyenoord win 5-0 at FC Groningen on the opening weekend of the Eredivisie.
West Ham will play Romanian champions FC Astra Giurgiu in the Europa League play-off round.
AZ Alkmaar sporting director Mark Huiberts has dismissed reports that Tottenham are close to signing their striker Vincent Janssen as "nonsense".
Dutch striker Vincent Janssen says he is frustrated with AZ Alkmaar for turning down a £15m bid from Tottenham for his transfer.
With Sky sources indicating Tottenham have held talks with Vincent Janssen, we shed some light on last season's Eredivisie top scorer.
Tottenham have held talks with Eredivisie top scorer Vincent Janssen after AZ Alkmaar gave him permission to speak to Spurs.
Ajax moved a step closer to reclaiming the Eredivisie title on Sunday with a thumping 4-0 win over FC Twente.
AZ Alkmaar took a grip of fourth place in the Eredivisie with a 2-1 win over ADO Den Haag.
PSV Eindhoven returned to the top of the Eredivisie table after a 3-0 success at Roda JC sealed a third straight win.
Feyenoord tightened their grip on third place and a Europa League qualification spot with a 1-0 win at FC Twente.
Marko van Ginkel scored twice as PSV returned to the top of the Eredivisie table with a 4-2 win at AZ Alkmaar on Saturday.